Is anyone else having issues with routers losing connection to ACS after upgrading to v4.5.0?

I updated 27 routers last week and since then then I am getting emails daily from a number of these routers showing that they have lost connection.
I can connect directly to the routers and they are not showing any breaks to the ISP.

No other settings have changed, the routers would all have been on v4.4.6.2 previously.